Substituted glutaric acid lactones in the treatment of...

Details Substituted glutaric acid lactones in the treatment of... Substituted glutaric acid lactones in the treatment of...

C - Chemistry, Metallurgy

07

D

167/244, 260/356

C07D 309/30 (2006.01) A61K 31/365 (2006.01)

Patent

CA 1242209

Abstract Compounds of formula I Image are described which are useful to inhibit the formation of serum cholesterol by virtue of their ability to inhibit .beta.-hydroxy-.beta.-methylglutaryl-CoA(HMG CoA), the rate-controlling substance in the synthesis of serum cholesterol.

503535

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