Substituted guanidines and diaminonitroethenes, their...

Details Substituted guanidines and diaminonitroethenes, their... Substituted guanidines and diaminonitroethenes, their...

C - Chemistry, Metallurgy

07

C

C07C 279/28 (2006.01) A61K 31/04 (2006.01) A61K 31/275 (2006.01) C07C 211/52 (2006.01)

Patent

CA 2331299

Guanidine and diaminonitroethene derivatives represented by formula (I), wherein X, R1, R2, R3 and R4 are defined in the description, compositions thereof and methods for preparing the compounds described. The compounds are useful in the treatment of diseases of central nervous system, the cardiovascular system, pulmonary system, the gastrointestinal system and the endocrinological system.

Cette invention, qui a trait à des dérivés de guanidine et de diaminonitroéthène correspondant à la formule (I), X, R?1¿, R?2¿, R?3¿ et R?4¿ étant définis dans le descriptif, concerne également des compositions à base de ces substances ainsi que des procédés de préparation des composés décrits. Ces composés s'avèrent des plus utiles en matière de traitement de maladies du système nerveux central, du système cardio-vasculaire, du système pulmonaire, de l'appareil digestif et du système endocrinien.

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