Substituted guanidines having high binding to the sigma...

Details Substituted guanidines having high binding to the sigma... Substituted guanidines having high binding to the sigma...

C - Chemistry, Metallurgy

07

C

C07C 279/00 (2006.01) A61K 31/155 (2006.01) A61K 31/33 (2006.01) C07D 213/75 (2006.01) C07D 233/46 (2006.01) C07D 237/14 (2006.01) C07D 243/04 (2006.01) C07D 277/00 (2006.01) C07D 307/52 (2006.01) C07D 307/82 (2006.01) C07D 311/08 (2006.01) C07D 333/36 (2006.01)

Patent

CA 2083269

2083269 9118868 PCTABS00008 The invention relates to a method for the treatment or prophylaxis of psychosis, depression, hypertension, or anxiety in an animal by administering an effective amount of an N,N'-disubstituted guanidine or 2-imino-imidazolidine having a high affinity for the sigma receptor. The invention also relates to the novel guanidines of the invention as well as pharmaceutical compositions thereof.

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