Substituted heteroarylalkanoic acids and their use as aldose...

Details Substituted heteroarylalkanoic acids and their use as aldose... Substituted heteroarylalkanoic acids and their use as aldose...

C - Chemistry, Metallurgy

07

D

C07D 417/06 (2006.01) A61K 31/428 (2006.01) A61K 31/4436 (2006.01) A61P 3/10 (2006.01) A61P 19/06 (2006.01) C07C 229/30 (2006.01) C07D 207/32 (2006.01) C07D 207/337 (2006.01) C07D 211/90 (2006.01) C07D 213/26 (2006.01) C07D 213/30 (2006.01) C07D 213/57 (2006.01) C07D 213/61 (2006.01) C07D 213/80 (2006.01) C07D 309/38 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2466925

Disclosed are substituted heteroarylalkanoic acids acids of the following formula D-A-C (O)R' where D, A, and R' are defined herein. These compounds are useful in the treatement of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.

L'invention concerne des acides hétéroarylalkanoiques de formule D-A-C(O)R', dans laquelle D, A, et R' sont spécifiés dans le descriptif. Lesdits composés sont utiles dans le traitement de complications chroniques provenant du diabète mellitus. L'invention concerne également des compositions pharmaceutiques contenant lesdits composés, des méthodes de traitement employant lesdits composés, ainsi que des méthodes pour leur synthèse.

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