Substituted heterocycles and methods of use

Details Substituted heterocycles and methods of use Substituted heterocycles and methods of use

C - Chemistry, Metallurgy

07

D

C07D 239/36 (2006.01) A61K 31/513 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2672438

Selected compounds are effective for prophylaxis and treatment of diseases, such as c-met mediated diseases and/or HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like/ The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. (I)

L'invention concerne des composés sélectionnés qui sont efficace pour la prévention et le traitement de maladies, telles que des maladies induites par c-Met et/ou des maladies induites par HGF. L'invention concerne également de nouveaux composés, des analogues, des promédicaments et leurs sels de qualité pharmaceutique, des compositions pharmaceutiques et des méthodes de prévention et de traitement de maladies et de troubles, y compris le cancer et analogue. La présente invention concerne également des procédés destinés à la fabrication de ces composés et des produits intermédiaires utiles dans ces procédés.

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