C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/64 (2006.01) A61K 31/4412 (2006.01) A61K 31/50 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01) C07D 237/14 (2006.01)
Patent
CA 2610075
The invention relates to compounds of the formula (I), in which R1 , R2, R3, R4, R5, R6 and X have the meanings stated in the claims. The compounds are particularly suitable as antiarrhythmic active ingredients, in particular for the treatment and prophylaxis of atrial arrhythmias, for example atrial fibrillation (AF) or atrial flutter.
La présente invention concerne des composés de formule (I), dans laquelle R1, R2, R3, R4, R5, R6 et X ont les significations énoncées dans les revendications. Les composés sont particulièrement appropriés comme ingrédients actifs antiarythmiques, en particulier pour le traitement et la prophylaxie d~arythmies auriculaires, par exemple, une fibrillation auriculaire (FA) ou un flutter auriculaire.
Brendel Joachim
Christian Englert Heinrich
Pilorge Fabienne
Ruxer Jean-Marie
Wagner Michael
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis
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