Substituted heterocyclic compounds

Details Substituted heterocyclic compounds Substituted heterocyclic compounds

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) A61K 31/496 (2006.01)

Patent

CA 2513641

Disclosed are novel heterocyclic derivatives, useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction. The compounds are also useful in the treatment of diabetes, and for increasing HDL plasma levels in mammals.

L'invention concerne des nouveaux dérivés hétérocycliques convenant pour le traitement de divers états pathologiques, en particulier de maladies cardio-vasculaires telles que les arythmies auriculaires et ventriculaires, la claudication intermittente , l'angine de poitrine inversée, l'angor stable et instable, l'angine de poitrine provoquée par l'effort, l'insuffisance cardiaque congestive et l'infarctus du myocarde. Ces composés conviennent également pour le traitement du diabète et sont utiles pour augmenter la concentration plasmatique chez les mammifères.

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