Substituted heterocyclic compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 473/26 (2006.01) A61K 31/52 (2006.01) A61P 35/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2756871

The present invention relates to substituted heterocyclic compounds and substituted tetrahydroisoquinoline com-pounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions contain-ing substituted benzodiazepine compounds and substituted tetrahydroisoquinoline compounds and methods of treating cell prolif-erative disorders, such as cancer, by administering these compounds or pharmaceutical compositions to subjects in need thereof.

La présente invention porte sur des composés hétérocycliques substitués et sur des composés tétrahydroisoquinoline substitués et sur des procédés de synthèse de ces composés. La présente invention porte également sur des compositions pharmaceutiques contenant des composés benzodiazépine substitués et des composés tétrahydroisoquinoline substitués et sur des procédés de traitement de troubles prolifératifs cellulaires, tels que le cancer, par l'administration de ces composés ou de ces compositions pharmaceutiques à des sujets en ayant besoin.

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