Substituted hexahydroarylquinolizines

C - Chemistry – Metallurgy – 07 – D

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C07D 455/00 (2006.01) C07D 471/20 (2006.01) C07D 471/22 (2006.01) C07D 491/22 (2006.01) C07D 495/22 (2006.01) C07D 513/22 (2006.01)

Patent

CA 1288435

5793S/5249A 17393IA TITLE OF THE INVENTION SUBSTITUTED HEXAHYDROARYLQUINOLIZINES ABSTRACT OF THE DISCLOSURE Certain substituted hexahydroarylquinoli- zines and pharmaceutically acceptable salts thereof are peripherally selective .alpha.2-adrenoceptor antagonists. The compounds are adapted to be employed for the treatment of certain pathological disorders such as hypertension, diabetes, disorders involving platelet aggregation and the like without side effects attributable to effect on the central nervous system.

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