Substituted hydantoins

Details Substituted hydantoins Substituted hydantoins

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) A61K 31/4184 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2695956

This invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, and R6 are described in this application. These compounds inhibit the enzymes MEK 1 and MEK 2, protein kinases that are components of the MAP kinase signal transduction pathway. As such the compounds have anti-hyperproliferative cellular activity and are thus useful in the treatment of cell proliferative disorders, such as cancer.

Cette invention porte sur des composés représentés par la formule (I) ou sur les sels pharmaceutiquement acceptables de ces composés. Dans cette formule, R1, R2, R3, R4, R5 et R6 sont tels que décrits dans cette demande. Ces composés inhibent les enzymes MEK 1 et MEK 2, les protéines kinases qui sont des composants de la voie de transduction de signal MAP kinase. En tant que tels, les composés ont une activité cellulaire anti-hyperproliférative et sont par conséquent utiles dans le traitement de troubles de la prolifération cellulaire, tels que le cancer.

Affiliated with

Also associated with

Rating

Substituted hydantoins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted hydantoins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted hydantoins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1501881