C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/12 (2006.01) A61K 31/427 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2576599
The present invention relates to compounds of the formula (I), which are useful in treating diseases characterized by, the hyperactivity of MEK. Accordingly the compounds are useful in the treatment of diseases, such as, cancer, cognative and CNS disorders and inflammatory/autoimmune diseases.
La présente invention a trait à des composés de formule (I), utiles dans le traitement de maladies caractérisées par l'hyperactivité de la protéine kinase activée par des agents mitogènes/la kinase régulée par un signal extracellulaire (MEK). Par conséquent, les composés sont utiles dans le traitement de maladies telles que le cancer, les troubles cognitifs et du système nerveux central et des maladies inflammatoires/auto-immunes.
Chu Xin-Jie
Fotouhi Nader
Huby Nicholas John Silvester
Kong Norman
Mcdermott Lee Apostle
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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