C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/74 (2006.01) A61K 31/4166 (2006.01) A61P 35/00 (2006.01) C07D 233/78 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2707650
The present invention relates to compounds of the formula (I) methods for the preparation thereof, and methods for their use. The compounds are useful in treating diseases characterized by the hyperactivity of MEK. Accordingly the compounds are useful in the treatment of diseases, such as cancer, cognitive and CNS disorders, and inflammatory/autoimmune diseases.
La présente invention concerne des composés de formule (I), des procédés pour leur préparation, et des procédés pour leur utilisation. Les composés sont utiles dans le traitement de maladies caractérisées par l'hyperactivité de la MEK. Les composés sont par conséquent utiles dans le traitement de maladies, telles que le cancer, les troubles cognitifs et du SNC, et les maladies inflammatoires/auto-immunes.
Chen Shaoqing
Huby Nicholas John Silvester
Kong Norman
Moliterni John Anthony
Morales Omar Jose
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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