Substituted imidazole 4-carboxamides as cholecystokinin-1...

Details Substituted imidazole 4-carboxamides as cholecystokinin-1... Substituted imidazole 4-carboxamides as cholecystokinin-1...

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) A61K 31/496 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2649927

Certain novel substituted imidazole 4-carboxamides are ligands of the human cholecystokinin receptor and, in particular, are selective ligands of the human cholecystokinin-1 receptor (CCK-1R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of CCK-1R, such as obesity, and diabetes.

L'invention concerne certains nouveaux imidazole 4-carboxamides substitués qui sont des ligands du récepteur de cholécystokinine humain et, en particulier, des ligands sélectifs du récepteur de cholécystokinine-1 (CCK-1R) humain. On les utilise donc pour traiter, combattre ou prévenir des maladies et des troubles qui réagissent à la modulation de CCK-1R, par exemple l'obésité et les différents types de diabète.

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