Substituted imidazoles as modulators of multi-drug resistance

Details Substituted imidazoles as modulators of multi-drug resistance Substituted imidazoles as modulators of multi-drug resistance

C - Chemistry, Metallurgy

07

D

C07D 233/64 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2179086

This invention relates to compounds of Formula 1 which are pharmacologically useful for the treatment of cancer through sensitization of multi-drug resistant cancer cells to chemotherapeutic agents. (see fig.I) wherein R1, R2, R3, and R4 are, for example, alkyl, aryl, etc., which are defined more specifically hereinafter.

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