Substituted iminoderivatives of dihydrobenzopyran and...

Details Substituted iminoderivatives of dihydrobenzopyran and... Substituted iminoderivatives of dihydrobenzopyran and...

C - Chemistry, Metallurgy

07

D

260/328, 260/356

C07D 311/68 (2006.01) C07D 311/96 (2006.01) C07D 335/04 (2006.01) C07D 335/06 (2006.01)

Patent

CA 1197253

Abstract of the Disclosure The invention relates to substituted iminoderivatives of 4H-2,3- dihydrobenzopyran and 4H-2,3-dihydrobenzothiopyran of formula I Image wherein X is -O- or -S-; each of R1, R2 and R3, being the same or different, is hydrogen, C1-C10 alkyl or phenyl; or R1 and R2, taken together, form a C5-C7 cycloakyl ring; R4 is hydrogen or C1-C6 alkyl; R6 is -OR10 or -SR10, wherein R10 is hydrogen or C1-C6 alkyl; R5 is C1-C10 alkyl, C2-C10 alkenyl or C3-C7 cycloalkyl, wherein the alkyl, alkenyl and cycloalkyl groups are unsubstituted or substituted by one or more substituents chosen from the group consisting of halogen, oxo, -OR10, -SR10, -COR10, -OCOR10, -COOR10 and Image wherein each of the groups R10, being the same or different, is as defined above; one of R7, R8 and R9 is C1-C12 alkyl and the others, which may be the same or different, are hydrogen or C1-C12 alkyl, and the pharmaceutical- ly acceptable salts thereof. The compounds are active on the central nervous system, particularly us depressants, i.e. as sedatives, anticonvulsive agents, minor tranquilizers and as sleep inducing agents.

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