Substituted indazole derivatives active as kinase inhibitors

Details Substituted indazole derivatives active as kinase inhibitors Substituted indazole derivatives active as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 231/56 (2006.01) A61K 31/33 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2693901

Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer.

L'invention porte sur des dérivés d'indazole substitués représentés par la formule (I) et sur des sels pharmaceutiquement acceptables de ceux-ci définis dans la description ainsi que sur un procédé permettant de les préparer et sur des compositions pharmaceutiques les comprenant. Les composés de l'invention peuvent être utiles dans le traitement de maladies associées à une activité protéine kinase dérégulée comme le cancer.

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