Substituted indazole derivatives active as kinase inhibitors

Details Substituted indazole derivatives active as kinase inhibitors Substituted indazole derivatives active as kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 231/56 (2006.01) A61K 31/4162 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2673095

Substituted indazole derivativesof formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a dysregulated protein kinase activity, like cancer formula (I).

La présente invention concerne des dérivés d'indazole substitués de formule (I) et leurs sels pharmaceutiquement acceptables, tels que définis dans le mémoire descriptif, leur procédé de préparation et des compositions pharmaceutiques qui les comprennent. Les composés selon l'invention ont une utilisation thérapeutique pour le traitement de maladies associée à une activité protéine-kinase déréglée telles que le cancer. Formule (I)

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