Substituted indoles and their use as hcv inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 409/12 (2006.01) A61K 31/404 (2006.01) C07D 209/08 (2006.01) C07D 209/18 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2501547

The present invention comprises indole-derivatives that are inhibitors of HCV. Composition comprising the compounds in combination with a pharmaceutically acceptable carrier are also disclosed, as are methods of using the compounds and compositions to inhibit HCV infection of a cell, particular in the form of treating HCV infection in a mammal.

L'invention se rapporte à des dérivés d'indole qui inhibent le virus de hépatite C (VHC). Cette invention concerne en outre des compositions contenant ces composés en association avec un excipient pharmaceutiquement acceptable, ainsi que des procédés d'utilisation de ces composés et compositions pour inhiber l'infection d'une cellule par le VHC, en particulier des procédés permettant de traiter un mammifère infecté par le VHC.

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