Substituted indoles for modulating nfkb activity

Details Substituted indoles for modulating nfkb activity Substituted indoles for modulating nfkb activity

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) C07D 209/08 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2389165

The invention relates to compounds of formula (I) which are suitable for the production of medicaments for the prophylaxis and treatment of disease states, the course of which involves increased NFkB activity. The compounds are specific IkB-kinase inhibitors.

L'invention concerne des composés de la formule (I) s'utilisant pour produire des médicaments pour assurer la prophylaxie et le traitement d'affections à l'évolution desquelles participe une activité renforcée du NFkB. Ces composés sont des inhibiteurs spécifiques de la IkB-kinase.

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