Substituted indoles, pharmaceutical compositions containing...

Details Substituted indoles, pharmaceutical compositions containing... Substituted indoles, pharmaceutical compositions containing...

C - Chemistry, Metallurgy

07

D

C07D 209/42 (2006.01) A61K 31/343 (2006.01) A61K 31/404 (2006.01) A61K 31/407 (2006.01) A61K 31/423 (2006.01) A61K 31/427 (2006.01) A61K 31/428 (2006.01) A61K 31/4709 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) C07D 209/00 (2006.01) C07D 209/48 (2006.01) C07D 317/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/04 (2006.01) C07D 405/10 (2006.01) C07D 405/12 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01) C07D

Patent

CA 2427499

Disclosed are substituted indoles, pharmaceutical compositions containing such indoles, and their use in treating or preventing PPAR-.gamma. mediated diseases or conditions, such as osteopenia, osteoporosis, cancer, diabetes and atherosclerosis.

Cette invention se rapporte à des indoles substituées, à des compositions pharmaceutiques contenant ces indoles et à leur utilisation pour traiter ou prévenir les affections ou les états à médiation par PPAR-.gamma., tels que l'ostéopénie, l'ostéoporose, le cancer, le diabète et l'athérosclérose.

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