Substituted indoles, process for their preparation and...

C - Chemistry – Metallurgy – 07 – D

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C07D 209/42 (2006.01) A61K 31/395 (2006.01) C07D 401/00 (2006.01) C07D 403/02 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/06 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2123267

PRECIS Composés de formule générale (I): (I) Image dans laquelle: - X représente O ou S, - X' représente O, S ou H2, - et R1, R2, R3 et R4 sont tels que définis dans la description. Ces composés trouvent leur application en thérapeutique dans le traitement ou la prévention des affections dues ou reliées à des phénomènes de peroxydation et notamment les désordres ischémiques cérébraux, rénaux ou cardiaques et les maladies métaboliques notamment l'athérome et l'artériosclérose, ainsi que l'inflammation.

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