Substituted indolizines and derivatives as cns agents

Details Substituted indolizines and derivatives as cns agents Substituted indolizines and derivatives as cns agents

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4353 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2585967

Compounds of formula (I) of pharmaceutically acceptable salts thereof are provided: formula (I), which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions containing the compounds, can be used to treat a variety of central nervous system disorders such as schizophrenia.

L'invention porte sur des composés de formule (I) ou sur leurs sels acceptables d'un point de vue pharmaceutique, ces composés étant des agonistes ou des agonistes partiels du sous-type 2C des récepteurs de la sérotonine du cerveau. Les composés et les compositions contenant les composés peuvent être utilisés pour traiter différents troubles du système nerveux central tels que la schizophrénie.

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