Substituted isoquinoline derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 401/06 (2006.01) C07D 217/20 (2006.01) C07D 217/26 (2006.01) C07D 241/08 (2006.01) C07D 295/205 (2006.01) C07D 295/24 (2006.01)

Patent

CA 1243028

ABSTRACT The substituted isoquinoline derivatives of the formula Image I wherein R is lower alkoxy, n is the integer zero or 1 and A is one of the groups < Image (a), (b), (c), (d), (e), Image (f), (g), wherein R1 is phenyl, halophenyl, lower-alkylphenyl or lower-alkoxyphenyl, and the pharmaceutically acceptable acid addition salts thereof can be used in the treatment and control of cere- brovascular disorders and hypertension. They can be pre- pared according to methods known per se.

454531

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