Substituted methyl aryl or heteroaryl amide compounds

Details Substituted methyl aryl or heteroaryl amide compounds Substituted methyl aryl or heteroaryl amide compounds

C - Chemistry, Metallurgy

07

C

C07C 235/42 (2006.01) A61K 31/166 (2006.01) A61K 31/4412 (2006.01) A61P 29/00 (2006.01) C07D 213/89 (2006.01)

Patent

CA 2565813

This invention provides a compound of the formula (I), wherein X represents a carbon atom or the like: Y represents imino, or the like: R1 represents an alkyl group having from 1 to 6 carbon atoms or the like: R2 and R3 independently represents a hydrogen atom or the like. These compounds are useful for the treatment of disease conditions mediated by prostaglandin such as pain, or the like in mammalian. This invention also provides a pharmaceutical composition comprising the above compound.

L'invention concerne un composé de la formule (1): dans laquelle X représente un atome de carbone ou analogue; Y représente un imino ou analogue; R?1¿ représente un groupe alkyle renfermant de 1 à 6 atomes de carbone ou analogue; R?2¿ et R?3¿ représentent indépendamment un atome d'hydrogène ou analogue. Les composés de l'invention sont utilisés dans le traitement d'états pathologiques médiés par la prostaglandine tels que la douleur ou analogue chez des mammifères. L'invention porte également sur une composition pharmaceutique comprenant le composé précité.

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