Substituted morphinans and methods of their use

Details Substituted morphinans and methods of their use Substituted morphinans and methods of their use

C - Chemistry, Metallurgy

07

D

C07D 489/08 (2006.01) A61K 31/485 (2006.01) A61K 45/08 (2006.01) A61P 25/04 (2006.01) C07D 489/06 (2006.01)

Patent

CA 2597410

Novel 4,5-.alpha. epoxy-morphinan compounds are disclosed. Pharmaceutical compositions containing the 4,5-.alpha. epoxy-morphinan compounds and methods of their pharmaceutical uses are also disclosed. The compounds disclosed are useful, inter alia, as modulators of opioid receptors.

La présente invention a trait à de nouveaux composés à base de 4,5-a époxy-morphinane. L'invention a également trait à des compositions contenant des composés à base de 4,5-a époxy-morphinane et à des procédés de leurs utilisations pharmaceutiques. Les composés de l'invention sont utiles, entre autres, en tant que modulateurs de récepteurs opioïdes.

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