Substituted n-aliphatic-n-aromatic...

Details Substituted n-aliphatic-n-aromatic... Substituted n-aliphatic-n-aromatic...

C - Chemistry, Metallurgy

07

C

C07C 217/52 (2006.01) A61K 31/135 (2006.01) A61K 31/33 (2006.01) C07C 215/08 (2006.01) C07C 215/12 (2006.01) C07C 215/16 (2006.01) C07C 215/50 (2006.01) C07C 215/76 (2006.01) C07C 217/16 (2006.01) C07C 217/20 (2006.01) C07C 217/30 (2006.01) C07C 217/54 (2006.01) C07C 217/58 (2006.01) C07C 217/82 (2006.01) C07C 217/90 (2006.01) C07C 229/30 (2006.01) C07D 213/74 (2006.01) C07D 307/14 (2006.01) C07D 309/14 (2006.01) C07D 493/08 (2006.01)

Patent

CA 2345108

The invention relates to substituted N-Aliphatic-N-Aromatic tertiary- Heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis, dyslipidemia, and other coronary artery disease.

L'invention concerne des composés à base d'hétéroalkylamines tertiaires N-aliphatiques-N-aromatiques substituées, utiles comme inhibiteurs de l'activité de la protéine de transfert de l'ester de cholestéryle (CETP, protéine de transfert des lipides plasmatiques 1), ainsi que des composés, des compositions et des méthodes permettant de traiter l'athérosclérose, les dyslipidémies et d'autres maladies des artères coronaires.

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