Substituted n-glycosylamides, process for their preparation,...

Details Substituted n-glycosylamides, process for their preparation,... Substituted n-glycosylamides, process for their preparation,...

C - Chemistry, Metallurgy

07

H

167/199, 260/229

C07H 5/06 (2006.01) A61K 31/70 (2006.01) C07H 15/12 (2006.01)

Patent

CA 1321993

Substituted N-glycosylamides, process for their prepar- ation, and their use as medicaments A b s t r a c t The invention relates to new N-glycosylamides of the general formula I Image in which R1 denotes a saturated alkyl radical or a singly, doubly or triply unsaturated alkenyl radical having up to 50 carbon atoms, R2 denotes a saturated alkyl radical or a singly, doubly or triply unsaturated alkenyl radical having up to 50 carbon atoms, A represents -CO- or represents a group Image , in which R3 represents hydrogen, C1-C7-alkyl, hydroxy- methyl, 1-hydroxyethyl, mercaptomethyl, 2-methyl- thioethyl, 3-aminopropyl, 3-ureidopropyl, 3-guani- dylpropyl, 4-aminobutyl, carboxymethyl, carbamoyl- methyl, 2-carboxyethyl, 2-carbamoylethyl, benzyl, 4-hydroxybenzyl, 3-indolylmethyl or 4-imidazolyl- methyl, and n represents 0 to 10, and which are substituted in the sugar residue with an amino acid residue, as well as process for their prepara- tion and their use as medicaments. Le A 25 870

596719

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