Substituted n-phenyl sulfonamide bradykinin antagonists

Details Substituted n-phenyl sulfonamide bradykinin antagonists Substituted n-phenyl sulfonamide bradykinin antagonists

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01)

Patent

CA 2509881

Disclosed are certain substituted N-phenylsulfonamide derivatives and related compounds. These compounds are useful as bradykinin antagonists to relieve adverse symptoms in mammals mediated, at least in part, by bradykinin including pain, inflammation, bronchoconstriction, cerebral edema, etc.

L'invention concerne certains dérivés à substitution N-phénylsulfonamide et des composés associés. Ces composés sont utilisés comme antagonistes de la bradykinine afin de soulager des symptômes indésirables chez les mammifères induits au moins en partie par la bradykinine, tels que la douleur, les inflammations, la bronchoconstriction, l'oedème cérébral, etc.

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