Substituted n-phenylpiperidines and drugs therefrom

Details Substituted n-phenylpiperidines and drugs therefrom Substituted n-phenylpiperidines and drugs therefrom

C - Chemistry, Metallurgy

07

D

C07D 211/26 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 211/56 (2006.01) C07D 211/58 (2006.01) C07D 401/02 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2063030

Substituted N-phenylpiperid- ines I (see formula I) (R1 = H, NO2, CN, halogen, C1-C4-alkyl, CF3, OCF3, OH, CH2OH, COOH, CHO, NH-CHO, NH2, CO-NH2, 5-tetrazinyl, R4-O-, R4-O-CH2-, R4-O-CO-, R4-CO-, R4-NH-CO, R4-CO-NH-, R4-SO2-NH-; R2 = H, NO2, halogen, C1-C4-alkyl or R4-O-; (see formula II) (see formula III) (see formula IV) (see formula V) (see formula VI) (see formula VII) (see formula VIII) R4 = C1-C4-alkyl or phenyl which can carry one of the R2 radicals; R5, R6, H or one of the R4 radicals; R7 = one of the R1 radicals; n = 0 or 1; m = 1 or 2; with the proviso that R3 is (see formula IX) only when n is 1, and the optical isomers in the case of optical isomerism, and the physiologically tolerated acid addition salts, are suitable as drugs.

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