Substituted oxadiazoles and thiadiazoles, and methods of...

Details Substituted oxadiazoles and thiadiazoles, and methods of... Substituted oxadiazoles and thiadiazoles, and methods of...

C - Chemistry, Metallurgy

07

D

260/308.3, 260/3

C07D 271/06 (2006.01) C07C 335/28 (2006.01) C07D 271/07 (2006.01) C07D 285/08 (2006.01) C07D 309/12 (2006.01)

Patent

CA 1172640

Abstract of Disclosure Compounds of the formula Image (I) wherein R1 is hydrogen, halogen, or alkyl, R2 is halogen or alkyl, R3 is hydrogen, acyl, or saturated or unsaturated alkyl, R4 and R5 are individually hydrogen or alkyl, wherein all alkyl and acyl groups are branched or straight-chain and each contains 1 to 4 carbon atoms, X is oxygen, nitrogen, or sulfur, Y is oxygen or nitrogen, and -X-Y- is -O-N-, -N-O-, or -S-N-, or salts of the above, with certain exceptions. Methods of preparation of the compounds, as well as their use as anti-hypertensives are also disclosed.

380733

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