Substituted oxadiazolidinediones als pai-1 inhibitors

Details Substituted oxadiazolidinediones als pai-1 inhibitors Substituted oxadiazolidinediones als pai-1 inhibitors

A - Human Necessities

61

K

A61K 31/4245 (2006.01) A61P 7/02 (2006.01) C07D 271/06 (2006.01) C07D 413/02 (2006.01) C07D 413/06 (2006.01)

Patent

CA 2538671

The present invention relates generally to substituted oxadiazolidinediones of the Formula (I); wherein R1 is hydrogen or -(CH2)nCOOH; n is an integer from 1 to 3; X is Formula (A), Formula (B), Formula (C) or Formula (D); as inhibitors of PAI-1.

L'invention concerne en général des oxadiazolidinediones substitués utilisés comme inhibiteurs des PAI-1 et représentés par la formule (I) dans laquelle R¿1? représente hydrogène ou -(CH¿2?)¿n?COOH; n est un nombre entier compris entre 1 et 3; et X représente les formules (A), (B), (C) ou (D).

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