C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/06 (2006.01) A61K 31/496 (2006.01) A61P 7/02 (2006.01) C07D 241/08 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 409/06 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2382755
This invention is directed to oxoazaheterocyclyl compounds which inhibit Factor Xa, to oxoazaheterocyclyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa.
La présente invention se rapporte à des composés d'oxoazahétérocyclyle qui inhibent le facteur Xa, à des composés d'oxoazahétérocyclyle qui inhibent le facteur Xa et le facteur IIa, à des compositions pharmaceutiques contenant les composés précités, à des intermédiaires utilisés pour préparer ces composés, à un procédé permettant d'inhiber directement le facteur Xa et à un procédé permettant d'inhiber directement et simultanément le facteur Xa et le facteur IIa.
Becker Michael R.
Burns Christopher J.
Choi-Sledeski Yong Mi
Condon Stephen M.
Davis Roderick S.
Aventis Pharmaceuticals Inc.
Aventis Pharmaceuticals Products Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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