Substituted oxotremorine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 207/26 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/445 (2006.01) A61K 31/695 (2006.01) C07D 207/27 (2006.01) C07D 207/273 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 521/00 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2066856

31, 636 SUBSTITUTED OXOTREMORINE DERIVATIVES ABSTRACT OF THE INVENTION This disclosure describes novel substituted oxotremorine derivatives of formula I having nitrogen, oxygen or sulfur groups and the prodrug forms of these derivatives. The compounds have cholinergic activity. Also disclosed are methods for treating diseases of the central nervous system in mammals employing the compounds, pharmaceutical preparations containing the compounds and the processes for the production of the compounds. Image FORMULA I

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