Substituted phenol derivatives as analgesics

Details Substituted phenol derivatives as analgesics Substituted phenol derivatives as analgesics

A - Human Necessities

61

K

A61K 31/055 (2006.01) A61K 31/136 (2006.01) A61K 31/166 (2006.01) A61K 31/167 (2006.01) A61P 25/04 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2632561

The present invention concerns the use of compounds derived from the anaethetic propofol that are useful as analgesics. The compounds act as activators of glycine receptors and may have greater activity at glycine receptors in the peripheral nervous system than at GABA receptors in the central nervous system.

La présente invention concerne l'utilisation de composés dérivés de l'anesthésique propofol qui sont utiles en tant qu'analgésiques. Les composés agissent en tant qu'activateurs de récepteurs de glycine et peuvent avoir une activité plus élevée au niveau de récepteurs de glycine dans le système nerveux périphérique qu'au niveau de récepteurs de GABA dans le système nerveux central.

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