Substituted phenoxybenzamides

Details Substituted phenoxybenzamides Substituted phenoxybenzamides

C - Chemistry, Metallurgy

07

C

C07C 307/10 (2006.01) A61K 31/16 (2006.01) A61P 35/00 (2006.01) C07C 237/44 (2006.01) C07C 271/28 (2006.01) C07C 303/34 (2006.01) C07C 311/00 (2006.01) C07C 311/08 (2006.01) C07C 317/18 (2006.01) C07D 207/08 (2006.01) C07D 231/18 (2006.01) C07D 233/84 (2006.01) C07D 261/18 (2006.01) C07D 285/06 (2006.01) C07D 295/16 (2006.01) C07D 295/26 (2006.01) C07D 307/68 (2006.01) C07D 333/38 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2720818

The present invention relates to substituted phenoxybenzamide compounds of general formula (I) : in which R1, R2, R3, R4, R5, X, R6 and q are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper- proliferative and /or angiogenesis disorder, as a sole agent or in combination with other active ingredients.

La présente invention concerne des composés phénoxybenzamides substitués représentés par la formule générale (I) : dans laquelle R1, R2, R3, R4, R5, X, R6 et q sont tels que définis dans les revendications. La présente invention concerne également des procédés de fabrication desdits composés, des compositions et des combinaisons pharmaceutiques comportant lesdits composés et l'utilisation desdits composés pour la fabrication d'une composition pharmaceutique pour le traitement ou la prophylaxie d'une maladie, en particulier d'un trouble hyperprolifératif et/ou d'angiogenèse, comme seul agent ou en combinaison avec d'autres ingrédients actifs.

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