Substituted phenyl farnesyltransferase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 233/54 (2006.01) A61K 31/33 (2006.01) A61P 43/00 (2006.01) C07D 213/30 (2006.01) C07D 213/36 (2006.01) C07D 213/38 (2006.01) C07D 213/57 (2006.01) C07D 213/74 (2006.01) C07D 231/12 (2006.01) C07D 249/04 (2006.01) C07D 249/08 (2006.01) C07D 277/24 (2006.01) C07D 277/28 (2006.01) C07D 277/30 (2006.01) C07D 333/16 (2006.01) C07D 333/24 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 409/10 (2006.01) C07D 409/12 (2006.01) C07D 413

Patent

CA 2407093

Compounds of formula (I) or pharmaceutically acceptable salts thereof, inhibit farnesyltransferase. Methods for making the compounds, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds are disclosed.

L'invention concerne des composés de formule (I) ou des sels correspondants acceptables pharmaceutiquement qui inhibent la farnésyltransférase. Cette invention concerne également des méthodes de fabrication des composés, des compositions pharmaceutiques renfermant les composés, et des méthodes de traitement utilisant les composés.

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