Substituted phenyl hydrazino-pyridazines

C - Chemistry – Metallurgy – 07 – D

Patent

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260/264.1

C07D 237/20 (2006.01)

Patent

CA 1071205

ABSTRACT OF THE DISCLOSURE Compounds are disclosed which may be represented by the following formula: Image FORMULA I wherein R1 or R2 is hydrogen, the other group being hydrogen, methyl, ethyl, propyl, isopropyl, fluoro, chloro, bromo, hydroxy, methoxy, hydroxymethyl, cyano, nitro or amino; R3 is hydrogen or methyl; and R4 is isopropyl, tertiary butyl or phenylethyl; and pharmaceutically acceptable acid addition salts thereof. The compounds disclosed find use in the treatment of angina pectoris, cardiac arrhythmias and hypertension.

253703

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