Substituted phenylpyrimidines useful in the treatment of cns...

Details Substituted phenylpyrimidines useful in the treatment of cns... Substituted phenylpyrimidines useful in the treatment of cns...

C - Chemistry, Metallurgy

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C07D 239/24 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/535 (2006.01) A61K 31/5377 (2006.01) C07C 255/54 (2006.01) C07C 255/56 (2006.01) C07D 239/42 (2006.01) C07D 239/46 (2006.01) C07D 239/48 (2006.01) C07D 239/50 (2006.01) C07D 239/56 (2006.01) C07D 239/58 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2004747

A pyrimidine of formula (I): Image wherein: R1 is NH2, N-(C1-C6 alkyl)amino or N,N-di(C1-C6 alkyl)amino; R2 is NH2; R3 is trifluoromethyl or CH2X wherein X is hydroxy, C1-C6 alkoxy, phenoxy, benzyloxy or halo; R4 and R5 are each halo; and R6 to R8 are each hydrogen; or a pharmaceutically acceptable acid addition salt thereof.

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