Substituted phenylquinazoline derivatives

Details Substituted phenylquinazoline derivatives Substituted phenylquinazoline derivatives

C - Chemistry, Metallurgy

07

D

C07D 513/04 (2006.01) A61K 31/505 (2006.01) C07D 239/78 (2006.01)

Patent

CA 2090635

600-7167 A B S T R A C T : SUBSTITUTED PHENYLQUINAZOLINE DERIVATIVES The invention relates to substituted phenylquinazoline derivatives. It concerns the compounds of formula I Image wherein the substituents have various significances. They may be obtained by a process comprising dehydration, ring closure and/or alkylation, and optional recovery in racemic or optionally active, in free base or acid addition salt form. They possess pharmcolofical activity, in particular, they raise the blood serum high density lipoprotein level and are thus indicated for use in the treatment of atherosclerosis.

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