Substituted phthalides as anti-convulsive drugs

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 307/88 (2006.01) A61K 31/34 (2006.01) A61P 25/00 (2006.01) C07D 239/42 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2413752

The invention relates to compounds of formula (I): wherein R1 represents an alkyl or ureido group, R2 represents an alkyl group or a hydrogen atom, or R1 and R2 together form a 5- or 6-membered ring, R3 represents a group CN, NO2, NRaR'a, NRaSO2,R'aCZR5 or CZNRaR'a, R4 represents a hydrogen atom or a group R3.

L'invention concerne des composés de formule (I): dans laquelle R?1¿ représente un alkyle ou un groupe uréido, R?2¿ représente un groupe alkyle ou un atome d'hydrogène, ou R?1¿ et R?2¿ forment ensemble un cycle à 5 ou 6 éléments, R?3¿ signifie un groupe CN, NO¿2?, NR¿a?R'¿a?, NR¿a?SO¿2?R'¿a?, NR¿a?CZR¿5? ou CZNR¿a?R'¿a?, R?4¿ signifie un atome d'hydrogène ou un groupe R?3¿.

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