C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01) A61K 31/496 (2006.01) A61K 31/497 (2006.01) A61P 1/00 (2006.01) A61P 25/00 (2006.01) C07D 403/12 (2006.01)
Patent
CA 2616307
The invention relates to compounds of formula I or pharmaceutically acceptable salts or solvates thereof: where Ar1, Ar2, Hy, L, R1, m and n are as defined in the description. The invention also includes pharmaceutical compositions and uses thereof, processes for making the compounds, as well as methods for the medical treatment of mGluR5-mediated disorders.
La présente invention a pour objet des composés de formule I, des sels de qualité pharmaceutique desdits composés, ou des solvates de qualité pharmaceutique desdits composés : où Ar1, Ar2, Hy, L, R1, m et n sont tels que définis dans la description. L'invention inclut également des préparations pharmaceutiques et les emplois desdites préparations, des procédés de synthèse des composés, ainsi que des méthodes de traitement médical de troubles faisant intervenir mGluR5.
Edwards Louise
Isaac Methvin
Mcleod Donald
Slassi Abdelmalik
Xin Tao
Astrazeneca Ab
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Edwards Louise
Isaac Methvin
Mcleod Donald
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