C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/20 (2006.01) A61K 31/496 (2006.01) A61K 31/497 (2006.01) A61P 25/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2694911
The present invention provides selective 5-HT7 receptor antagonist compounds of Formula (I) and their use in the treatment of migraine: where A is C(H)= or N=; m is 0, 1 or 2; R1 is optionally substituted phenyl, optionally substituted pyrazol-4-yl; optionally substituted imidazolyl, optionally substituted pyridyl, or thienyl; R2 is hydrogen or methyl; and R3 and R4 are as defined herein.
L'invention porte sur des composés antagonistes sélectifs du récepteur 5-HT7, représentés par la formule I, et sur leur utilisation dans le traitement de la migraine (I) dans laquelle A représente C(H)= ou N=; m est 0, 1 ou 2; R1 est phényle éventuellement substitué, pyrazol-4-yle éventuellement substitué; imydazolyle éventuellement substitué, pyridyle éventuellement substitué, ou thiényle; R2 est hydrogène ou méthyle; et R3 et R4 sont tels que définis ici.
Cohen Michael Philip
Filla Sandra Ann
Hellman Sarah Lynne
Hollinshead Sean Patrick
Tidwell Michael Wade
Eli Lilly And Company
Gowling Lafleur Henderson Llp
LandOfFree
Substituted piperazinyl pyrazines and pyridines as 5-ht7... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted piperazinyl pyrazines and pyridines as 5-ht7..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted piperazinyl pyrazines and pyridines as 5-ht7... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1425149