Substituted piperidine derivative and medicine comprising...

Details Substituted piperidine derivative and medicine comprising... Substituted piperidine derivative and medicine comprising...

C - Chemistry, Metallurgy

07

D

C07D 211/58 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07D 401/00 (2006.01) C07D 401/12 (2006.01) C07D 409/00 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2179574

Disclosed herein is a substituted piperidine derivative represented by the following general formula (1): Image (1) wherein R1 means an aryl or heteroaryl group which may have at least one substituent, R2 denotes an alkyl, alkenyl or aralkyl group, R3 stands for a hydrogen atom or an alkyl group, and R4 is a hydrogen atom, an alkyl group, or an aryl, heteroaryl, aralkyl, aralkenyl or heteroaralkyl group which may have at least one substituent, or a salt thereof. A medicine including this compound is also disclosed. The compound has excellent anticholinergic effect and calcium antagonism and inhibits reflex bladder contraction and is hence useful for prophylaxis of and treatment for a urinary disturbance such as pollakiuria.

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