C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/445 (2006.01) A61K 31/451 (2006.01) A61K 31/4523 (2006.01) A61K 31/4725 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07D 211/28 (2006.01) C07D 211/34 (2006.01) C07D 401/12 (2006.01) C07D 498/04 (2006.01) C07K 5/06 (2006.01) C07K 5/078 (2006.01)
Patent
CA 2452328
Selected substituted piperidine compounds are effective for prophylaxis and treatment of diseases, such as obesity and the like. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving activation of the melanocortin receptor. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Selon cette invention, les composés de pipéridine substituée choisis sont efficaces dans la prophylaxie et dans le traitement des maladies telles que l'obésité ou analogue. Cette invention concerne de nouveaux composés, analogues, promédicaments et sels pharmaceutiquement acceptables de ces derniers, ainsi que de nouvelles compositions pharmaceutiques et méthodes de prophylaxie et de traitement de maladies et autres pathologies ou états impliquant l'activation du récepteur de la mélanocortine. Cette invention porte également sur des méthodes de préparation de tels composés et d'intermédiaires utilisés dans ces méthodes.
Croghan Michael
Doherty Elizabeth M.
Fotsch Christopher H.
Kelly Michael G.
M. Smith,duncan
Amgen Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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