C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/14 (2006.01) A61K 31/496 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2656398
In its many embodiments, the present invention discloses novel compounds, as inhibitors of HDM2 protein, methods for preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of treatment, prevention, inhibition, of one or more diseases associated with the HDM2 protein or P53 using such compounds or pharmaceutical compositions.
Dans ses nombreux modes de réalisation, La présente invention concerne des composés innovants inhibiteurs de protéines HDM2, des procédés de préparation de tels composés, des compositions pharmaceutiques incluant un ou plusieurs composés de ce genre et des procédés de traitement, de prévention, d'inhibition d'une ou plusieurs maladies associées à la protéine HDM2 ou à la P53 à l'aide de tels composés ou compositions pharmaceutiques.
Bogen Stephane L.
Doll Ronald J.
Gerald W. Shipps Jr.
Gibeau Craig R.
Guo Zhuyan
Albany Molecular Research Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
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