C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/20 (2006.01) A61K 31/495 (2006.01) A61K 31/497 (2006.01) A61P 7/02 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2372617
The invention relates to substituted polycyclic aryl and heteroaryl pyrazinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
L'invention concerne des composés de pyrazinone d'hétéroaryle et d'aryle polycyclique substitués, utilisés en tant qu'inhibiteurs des sérines protéases de la coagulation en cascade, et des composés, compositions et méthodes d'anticoagulothérapie destinés au traitement et à la prévention d'une variété d'états thrombotiques notamment des maladies des artères coronaires et cérébrovasculaires.
Case Brenda
Dice Tom
Fenton Rick
Franklin Gary W.
Hayes Michael J.
Pharmacia Corporation
Smart & Biggar
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