C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/20 (2006.01) A61K 31/495 (2006.01) A61P 7/02 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07K 5/06 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2409445
The invention relates to substituted polycyclic aryl and heteroaryl pyrazinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
L'invention concerne des composés d'aryle polycyclique substitué et de pyrazinone d'hétéroaryle utilisés comme inhibiteurs des sérine protéases de la coagulation, et des composés, des compositions et des méthodes destinés à la thérapie d'anticoagulation permettant de traiter et de prévenir plusieurs affections thrombotiques, notamment des maladies des artères coronariennes et cérébrovasculaires.
Case Brenda
Dice Tom
Fenton Rick
Franklin Gary W.
Hayes Michael J.
Pharmacia Corporation
Smart & Biggar
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