Substituted polycyclic aryl and heteroaryl pyridines useful...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/00 (2006.01) C07D 213/74 (2006.01) C07D 213/89 (2006.01)

Patent

CA 2430037

The present invention relates to compounds, and prodrugs thereof, composition and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.

La présente invention a trait à des composés, et des promédicaments de ceux-ci, à une composition et à des méthodes utiles dans la prévention et le traitement d'états thrombotiques chez des mammifères. Les composés selon la présente invention, et les promédicaments de ceux-ci, inhibent de manière sélective certaines protéases de la cascade de la coagulation.

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