Substituted propanolamine and morpholine derivatives and...

C - Chemistry – Metallurgy – 07 – D

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C07D 317/66 (2006.01) C07C 41/16 (2006.01) C07C 43/215 (2006.01) C07C 45/41 (2006.01) C07C 59/68 (2006.01) C07C 205/32 (2006.01) C07D 265/30 (2006.01) C07D 265/32 (2006.01) C07D 265/33 (2006.01) C07D 295/092 (2006.01) C07D 303/24 (2006.01) C07D 317/58 (2006.01)

Patent

CA 1128942

Abstract of the Disclosure The invention is compounds of formula I: Image (I) wherein n is 1 or 2; the or each R, which may be the same or different, is hydrogen; halogen; hydroxy; C1-C6alkoxy; -NO2; Image , wherein R5 and R6 are, independently, hydrogen or C1-C6alkyl, or two adjacent R groups, taken to- gether, form the -O-CH2-O- radical; R1 is hydrogen halogen or lower alkoxy; R2 is hydrogen or C1-C12alkyl; each of the groups R3 and R4, which may be identical or different, is hydrogen or C1-C6alkyl; or R2 and R4, taken to- gether, form the -CH2-CH2- radical. The compounds are useful for their effect on the central nervous system, particularly their anti-depressant effect.

319931

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