Substituted pyrazines, pyrimidines and pyridazines for use...

Details Substituted pyrazines, pyrimidines and pyridazines for use... Substituted pyrazines, pyrimidines and pyridazines for use...

C - Chemistry, Metallurgy

07

D

C07D 453/00 (2006.01) A61K 31/495 (2006.01) A61K 31/50 (2006.01) A61K 31/505 (2006.01) A61K 31/55 (2006.01) C07D 453/02 (2006.01) C07D 453/06 (2006.01) C07D 471/08 (2006.01)

Patent

CA 2058178

T1091Y ABSTRACT SUBSTITUTED PYRAZINES, PYRIMIDINES AND PYRIDAZINES FOR USE IN THE TREATMENT OF GLAUCOMA A class of pyrazine, pyrimidine and pyridazine derivatives, substituted by a non-aromatic azabicyclic ring system and optionally by up to two further substituents, is of use in the preparation of medicaments, especially formulations adapted for topical administration to the eye, suitable for the treatment of glaucoma and/or for reducing intraocular pressure.

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